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Br J Ophthalmol 1997;81:962-964 ( November )

Endogenous cortisol profile in patients with central serous chorioretinopathy

S P Garg, Tanuj Dada, Dinesh Talwar, N R Biswas

Dr R P Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi - 110029, India

Correspondence to: Dr T Dada.

Accepted for publication 4 June 1997

AIM---To study the endogenous cortisol levels in patients with central serous chorioretinopathy (CSCR).
METHODS---Endogenous cortisol levels in urine and plasma were determined in 30 patients with acute CSCR and compared with 30 age and sex matched controls.
RESULTS---The mean values of the 8 am plasma cortisol (29.97 µg/dl v 18.76 µg/dl), 11 pm plasma cortisol (22.03 µg/dl v 13.06 µg/dl), and 24 hour urine cortisol (11.01 mg/24 h v 7.39 mg/24 h) revealed significantly higher values in the patient group (p<0.001).
CONCLUSIONS---Increased levels of endogenous cortisol are present in patients with CSCR.

© 1997 by British Journal of Ophthalmology


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