This Article Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Add article to my folders Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Han, Y K Articles by Lee, J H Search for Related Content PubMed PubMed Citation Articles by Han, Y K Articles by Lee, J H

In vitro and in vivo study of lens refilling with poloxamer hydrogel

¹ Department of Ophthalmology, Seoul Municipal Boramae Hospital, Korea
² Department of Ophthalmology, Seoul National University College of Medicine, Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Korea
³ School of Agricultural Biotechnology, Seoul National University, Korea

Correspondence to:
Correspondence to:
Jin Hak Lee
Department of Ophthalmology, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-744, Republic of Korea; jjhlee{at}plaza.snu.ac.kr

Aim: To evaluate the compatibility of poloxamer hydrogel as a material for an injectable intraocular lens, in vivo and in vitro.

Methods: The appropriate concentration of poloxamer hydrogel was determined for injection by examining the transparency and gelling temperature of this material, assessing the lens capsule refilling technique, and studying the postoperative findings in a rabbit model.

Results: Poloxamer hydrogel showed excellent transparency and 25% was identified as an appropriate concentration for the lens refilling material. The authors developed a technique for injecting the material in vivo and obtained excellent short term results.

Conclusions: Poloxamer hydrogel was identified as an appropriate material for direct lens refilling, and the developed injection technique produced excellent short term results.

Keywords: injectable intraocular lens; lens refilling; poloxamer hydrogel; rabbit model

This article has been cited by other articles:

				M. Zhao, G. Thuret, S. Piselli, A. Pipparelli, S. Acquart, M. Peoc'h, J.-M. Dumollard, and P. Gain Use of Poloxamers for Deswelling of Organ-Cultured Corneas Invest. Ophthalmol. Vis. Sci., February 1, 2008; 49(2): 550 - 559. [Abstract] [Full Text] [PDF]

				G. Duncan, L. Wang, G. J. Neilson, and I. M. Wormstone Lens Cell Survival after Exposure to Stress in the Closed Capsular Bag Invest. Ophthalmol. Vis. Sci., June 1, 2007; 48(6): 2701 - 2707. [Abstract] [Full Text] [PDF]